{"id":11920,"date":"2024-12-06T10:00:24","date_gmt":"2024-12-06T03:00:24","guid":{"rendered":"https:\/\/chgcancercenter.com\/?p=11920"},"modified":"2024-12-17T23:01:11","modified_gmt":"2024-12-17T16:01:11","slug":"microplastics-and-breast-cancer-progression","status":"publish","type":"post","link":"https:\/\/chgcancercenter.com\/en\/microplastics-and-breast-cancer-progression\/","title":{"rendered":"Do Microplastics Trigger Breast Cancer Progression?"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"11920\" class=\"elementor elementor-11920\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53eb7dc6 e-flex e-con-boxed e-con e-parent\" data-id=\"53eb7dc6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1995faba elementor-widget elementor-widget-text-editor\" data-id=\"1995faba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1><span style=\"font-size: 24pt;\"><strong>Do Microplastics Trigger Breast Cancer Progression?<\/strong><\/span><\/h1><p class=\"translation-block\">Polypropylene microplastics (PP microplastics) are a major concern in environmental pollution, and emerging research suggests they may influence the progression of breast cancer. Here\u2019s how these tiny particles could impact cancer development:<\/p><h2><span style=\"font-size: 18pt;\"><b>1. Chronic Inflammation<\/b><\/span><\/h2><p class=\"translation-block\">PP microplastics can trigger an immune response, leading to chronic inflammation.<\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">This process releases cytokines, such as IL-6 and TNF-\u03b1, that promote cancer cell proliferation and metastasis.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Additionally, reactive oxygen species (ROS) generated during inflammation may damage DNA, increasing mutation risks.<\/li><\/ul><h2><span style=\"font-size: 18pt;\"><b>2. Cell Signaling Disruption<\/b><\/span><\/h2><p><span style=\"font-weight: 400;\">PP microplastics may activate pathways like:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">NF-\u03baB Pathway: Encourages inflammation and cancer survival.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">TGF-\u03b2 Signaling: Facilitates epithelial-to-mesenchymal transition (EMT), enabling cancer cells to invade other tissues.<\/li><\/ul><h2><span style=\"font-size: 18pt;\"><b>3. Hormonal Interference<\/b><\/span><\/h2><p class=\"translation-block\">Some plastic additives mimic estrogen, disrupting hormonal balance. Hormone-sensitive breast cancers may grow faster due to these endocrine-disrupting chemicals.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c0ac684 e-flex e-con-boxed e-con e-parent\" data-id=\"c0ac684\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0114591 elementor-widget elementor-widget-image\" data-id=\"0114591\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"428\" src=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2-768x513.jpg\" class=\"attachment-medium_large size-medium_large wp-image-11932\" alt=\"\u0e20\u0e32\u0e1e\u0e1b\u0e23\u0e30\u0e01\u0e2d\u0e1a\u0e17\u0e32\u0e07\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e41\u0e2a\u0e14\u0e07\u0e44\u0e21\u0e42\u0e04\u0e23\u0e1e\u0e25\u0e32\u0e2a\u0e15\u0e34\u0e01\u0e42\u0e1e\u0e25\u0e35\u0e42\u0e1e\u0e23\u0e1e\u0e35\u0e25\u0e35\u0e19\u0e17\u0e35\u0e48\u0e17\u0e33\u0e1b\u0e0f\u0e34\u0e01\u0e34\u0e23\u0e34\u0e22\u0e32\u0e01\u0e31\u0e1a\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e15\u0e49\u0e32\u0e19\u0e21 \u0e42\u0e14\u0e22\u0e40\u0e19\u0e49\u0e19\u0e01\u0e25\u0e44\u0e01\u0e15\u0e48\u0e32\u0e07\u0e46 \u0e40\u0e0a\u0e48\u0e19 \u0e01\u0e32\u0e23\u0e2d\u0e31\u0e01\u0e40\u0e2a\u0e1a\u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e2b\u0e22\u0e38\u0e14\u0e0a\u0e30\u0e07\u0e31\u0e01\u0e02\u0e2d\u0e07\u0e2e\u0e2d\u0e23\u0e4c\u0e42\u0e21\u0e19\" srcset=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2-768x513.jpg 768w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2-300x200.jpg 300w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2-18x12.jpg 18w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2-600x401.jpg 600w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2024\/12\/Do-Microplastics-Trigger-Breast-Cancer-Progression2.jpg 800w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-03fc15b e-flex e-con-boxed e-con e-parent\" data-id=\"03fc15b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36c3cc6 elementor-widget elementor-widget-text-editor\" data-id=\"36c3cc6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"font-size: 18pt; color: #000000;\"><b>4. Tumor Microenvironment Alteration<\/b><\/span><\/h2><p><span style=\"font-weight: 400; color: #000000;\">Microplastics can influence the tumor microenvironment by<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400; color: #000000;\">promoting angiogenesis (new blood vessel formation)<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400; color: #000000;\">that supports tumor growth and metastasis.<\/span><\/li><\/ul><h2><span style=\"font-size: 18pt; color: #000000;\"><b>5. Immune System Suppression<\/b><\/span><\/h2><p class=\"translation-block\">PP microplastics may inhibit immune cells like T cells and NK cells, allowing cancer cells to evade detection and spread more easily.<\/p><p class=\"translation-block\">While the connection between microplastics and breast cancer progression is still being studied, evidence suggests their role in inflammation, hormonal disruption, and immune suppression. Minimizing exposure to microplastics is crucial for long-term health.\n\nBy addressing environmental pollution and exploring safer alternatives, we can work towards reducing these risks in our daily lives.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-21fb3f8 e-flex e-con-boxed e-con e-parent\" data-id=\"21fb3f8\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-42eeeda elementor-widget elementor-widget-video\" data-id=\"42eeeda\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=jJF-9JBtY5w&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div 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target=\"_self\">+66638166058<\/a><\/p>\t\t\n\t\t<\/div>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc4a6ee e-flex e-con-boxed e-con e-child\" data-id=\"cc4a6ee\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c0616b5 e-con-full e-flex e-con e-child\" data-id=\"c0616b5\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e7c50bd elementor-widget elementor-widget-text-editor\" data-id=\"e7c50bd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: lineseedsansth;\">Request consultation for treatment plan<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9058c76 e-con-full e-flex e-con e-child\" data-id=\"9058c76\" data-element_type=\"container\" data-settings=\"{&quot;position&quot;:&quot;absolute&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d1e4874 elementor-widget elementor-widget-text-editor\" data-id=\"d1e4874\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/lin.ee\/sx9JJLJ\"><img decoding=\"async\" class=\"\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/th.png\" alt=\"\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e19\" width=\"115\" height=\"36\" border=\"0\" \/><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-549157e e-flex e-con-boxed e-con e-child\" data-id=\"549157e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\u0e44\u0e21\u0e42\u0e04\u0e23\u0e1e\u0e25\u0e32\u0e2a\u0e15\u0e34\u0e01 polypropylene \u0e2d\u0e32\u0e08\u0e01\u0e23\u0e30\u0e15\u0e38\u0e49\u0e19\u0e01\u0e32\u0e23\u0e25\u0e38\u0e01\u0e25\u0e32\u0e21\u0e02\u0e2d\u0e07\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e15\u0e49\u0e32\u0e19\u0e21\u0e1c\u0e48\u0e32\u0e19\u0e01\u0e32\u0e23\u0e2d\u0e31\u0e01\u0e40\u0e2a\u0e1a \u0e01\u0e32\u0e23\u0e23\u0e1a\u0e01\u0e27\u0e19\u0e23\u0e30\u0e1a\u0e1a\u0e2e\u0e2d\u0e23\u0e4c\u0e42\u0e21\u0e19 \u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e40\u0e1b\u0e25\u0e35\u0e48\u0e22\u0e19\u0e41\u0e1b\u0e25\u0e07\u0e2a\u0e31\u0e0d\u0e0d\u0e32\u0e13\u0e43\u0e19\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e40\u0e0b\u0e25\u0e25\u0e4c<\/p>","protected":false},"author":2,"featured_media":11936,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[162],"tags":[62,804,809,805,807,97,810,70,806,260,93,811,808,90,803],"class_list":["post-11920","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle-that-risks-cancer","tag-chg-cancer-center","tag-polypropylene-microplastics","tag-809","tag-805","tag-807","tag-97","tag-810","tag-breast-cancer","tag-806","tag-260","tag-93","tag-811","tag-808","tag-90","tag-803"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/11920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/comments?post=11920"}],"version-history":[{"count":0,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/11920\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media\/11936"}],"wp:attachment":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media?parent=11920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/categories?post=11920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/tags?post=11920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}