{"id":12398,"date":"2025-01-25T09:00:13","date_gmt":"2025-01-25T02:00:13","guid":{"rendered":"https:\/\/chgcancercenter.com\/?p=12398"},"modified":"2025-01-29T00:23:59","modified_gmt":"2025-01-28T17:23:59","slug":"systemic-therapy-liver-cancer-treatment","status":"publish","type":"post","link":"https:\/\/chgcancercenter.com\/en\/systemic-therapy-liver-cancer-treatment\/","title":{"rendered":"Systemic Therapy: A New Hope for Advanced Liver Cancer Treatment"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"12398\" class=\"elementor elementor-12398\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53eb7dc6 e-flex e-con-boxed e-con e-parent\" data-id=\"53eb7dc6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1995faba elementor-widget elementor-widget-text-editor\" data-id=\"1995faba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1><span style=\"font-size: 24pt;\"><strong>Systemic Therapy: A New Hope for Advanced Liver Cancer Treatment<\/strong><\/span><\/h1><p class=\"translation-block\">Systemic Therapy is a treatment approach for Hepatocellular Carcinoma (HCC) that uses medications to eliminate or control cancer cells throughout the body. Unlike local therapies such as surgery or Transarterial Chemoembolization (TACE), systemic therapy is not limited to targeting specific tumor sites.<\/p><h2><span style=\"font-size: 18pt;\"><b>Goals of Systemic Therapy in Liver Cancer Treatment<\/b><\/span><\/h2><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inhibit the growth of cancer cells<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow the spread of cancer<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shrink tumors and relieve symptoms<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prolong patient survival and improve quality of life<\/span><\/li><\/ul><h2><span style=\"font-size: 18pt;\"><b>Types of Systemic Therapy for Liver Cancer<\/b><\/span><\/h2><h3><span style=\"font-size: 14pt;\"><b>1. Targeted Therapy<\/b><\/span><\/h3><p><span style=\"font-weight: 400;\">Targeted therapy focuses on specific molecules and pathways involved in cancer growth, such as the formation of new blood vessels that feed tumors.<\/span><\/p><p><b>Examples of Drugs:<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Sorafenib (Nexavar): The first approved drug for advanced liver cancer, blocking blood vessel formation and cancer cell division.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Lenvatinib (Lenvima): An alternative first-line therapy with similar effectiveness to Sorafenib.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Regorafenib (Stivarga): Used for patients unresponsive to Sorafenib.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Cabozantinib (Cabometyx): For patients who failed previous treatments.<\/li><\/ul><h3><span style=\"font-size: 14pt;\"><b>2. Immunotherapy<\/b><\/span><\/h3><p><span style=\"font-weight: 400;\">Immunotherapy stimulates the body\u2019s immune system to destroy cancer cells by blocking proteins that allow cancer to evade immune detection.<\/span><\/p><p><b>Examples of Drugs:<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Atezolizumab + Bevacizumab: Combines immunotherapy with anti-angiogenic therapy, offering superior outcomes compared to targeted therapy alone.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Nivolumab (Opdivo): A PD-1 inhibitor that boosts immune response against cancer.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Pembrolizumab (Keytruda): Used for patients who do not respond to other treatments.<\/li><\/ul><h3><span style=\"font-size: 14pt;\"><b>3. Chemotherapy<\/b><\/span><\/h3><p class=\"translation-block\">Although not the main treatment for liver cancer due to cancer cell resistance, chemotherapy is sometimes combined with other therapies.<\/p><p><b>Examples of Drugs:<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Doxorubicin<\/b><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cisplatin<\/b><\/li><\/ul><p><span style=\"font-weight: 400;\">These drugs are typically used when no other treatments are effective or as part of TACE procedures.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-03fc15b e-flex e-con-boxed e-con e-parent\" data-id=\"03fc15b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36c3cc6 elementor-widget elementor-widget-text-editor\" data-id=\"36c3cc6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"color: #000000; font-size: 18pt;\"><b>Advantages of Systemic Therapy for Liver Cancer<\/b><\/span><\/h2><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Comprehensive Cancer Control: Effectively manages cancer spread throughout the body.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Suitable for Advanced Stages: Beneficial for cancer that has spread to blood vessels or other organs.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Combination Potential: Can be combined with other treatments like TACE or RFA for enhanced effectiveness.<\/li><\/ul><h2><span style=\"color: #000000; font-size: 18pt;\"><b>Limitations of Systemic Therapy<\/b><\/span><\/h2><ul><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Side Effects: May cause fatigue, appetite loss, diarrhea, or high blood pressure.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Varied Effectiveness: Not all patients respond equally to systemic therapy.<\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">High Costs: Some drugs are expensive and may not be covered by insurance.<\/li><\/ul><p class=\"translation-block\">Systemic therapy is a vital option for treating liver cancer, especially in advanced stages or when local therapies are ineffective. Targeted therapy and immunotherapy are now widely used for slowing disease progression and prolonging patient survival.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c0896a9 e-flex e-con-boxed e-con e-parent\" data-id=\"c0896a9\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7d86375 elementor-widget elementor-widget-video\" data-id=\"7d86375\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=tYxxR4VCDOU&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a93b92e e-flex e-con-boxed e-con e-parent\" data-id=\"a93b92e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-93ea625 elementor-widget elementor-widget-image\" data-id=\"93ea625\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"480\" src=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2.jpg\" class=\"attachment-large size-large wp-image-12404\" alt=\"\u0e20\u0e32\u0e1e\u0e1b\u0e23\u0e30\u0e01\u0e2d\u0e1a\u0e17\u0e32\u0e07\u0e01\u0e32\u0e23\u0e41\u0e1e\u0e17\u0e22\u0e4c\u0e02\u0e2d\u0e07\u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e40\u0e1b\u0e47\u0e19\u0e23\u0e30\u0e1a\u0e1a\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e15\u0e31\u0e1a \u0e41\u0e2a\u0e14\u0e07\u0e22\u0e32\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e41\u0e1a\u0e1a\u0e01\u0e33\u0e2b\u0e19\u0e14\u0e40\u0e1b\u0e49\u0e32\u0e2b\u0e21\u0e32\u0e22 \u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19\u0e1a\u0e33\u0e1a\u0e31\u0e14 \u0e41\u0e25\u0e30\u0e40\u0e04\u0e21\u0e35\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e17\u0e35\u0e48\u0e17\u0e33\u0e07\u0e32\u0e19\u0e17\u0e31\u0e48\u0e27\u0e23\u0e48\u0e32\u0e07\u0e01\u0e32\u0e22\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e04\u0e27\u0e1a\u0e04\u0e38\u0e21\u0e41\u0e25\u0e30\u0e17\u0e33\u0e25\u0e32\u0e22\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\" srcset=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2.jpg 800w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2-300x225.jpg 300w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2-768x576.jpg 768w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2-16x12.jpg 16w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/01\/Systemic-Therapy_-A-New-Hope-for-Advanced-Liver-Cancer-Treatment2-600x450.jpg 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-32e8f1d e-flex e-con-boxed e-con e-parent\" data-id=\"32e8f1d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18e9011 elementor-widget elementor-widget-ct_text_editor\" data-id=\"18e9011\" data-element_type=\"widget\" data-widget_type=\"ct_text_editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"ct_text_editor-18e9011\" class=\"ct-text-editor wow fadeInUp\" data-wow-delay=\"ms\">\n\t<div class=\"ct-item--inner\">\n\t\t<div class=\"ct-inline-css\"  data-css=\"\t        \t\t\t\">\n\n\t    <\/div>\n\t\t<div class=\"ct-text-editor elementor-clearfix\">\n\t\t\t<p class=\"translation-block\">For inquiry, please call <a href=\"tel:0638166058\" target=\"_self\">+66638166058<\/a><\/p>\t\t\n\t\t<\/div>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc4a6ee e-flex e-con-boxed e-con e-child\" data-id=\"cc4a6ee\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c0616b5 e-con-full e-flex e-con e-child\" data-id=\"c0616b5\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e7c50bd elementor-widget elementor-widget-text-editor\" data-id=\"e7c50bd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: lineseedsansth;\">Request consultation for treatment plan<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9058c76 e-con-full e-flex e-con e-child\" data-id=\"9058c76\" data-element_type=\"container\" data-settings=\"{&quot;position&quot;:&quot;absolute&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d1e4874 elementor-widget elementor-widget-text-editor\" data-id=\"d1e4874\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/lin.ee\/sx9JJLJ\"><img decoding=\"async\" class=\"\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/th.png\" alt=\"\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e19\" width=\"115\" height=\"36\" border=\"0\" \/><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-549157e e-flex e-con-boxed e-con e-child\" data-id=\"549157e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\u0e23\u0e39\u0e49\u0e08\u0e31\u0e01 Systemic Therapy \u0e17\u0e32\u0e07\u0e40\u0e25\u0e37\u0e2d\u0e01\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e15\u0e31\u0e1a\u0e23\u0e30\u0e22\u0e30\u0e25\u0e38\u0e01\u0e25\u0e32\u0e21 \u0e0a\u0e48\u0e27\u0e22\u0e0a\u0e30\u0e25\u0e2d\u0e01\u0e32\u0e23\u0e25\u0e38\u0e01\u0e25\u0e32\u0e21\u0e02\u0e2d\u0e07\u0e42\u0e23\u0e04\u0e41\u0e25\u0e30\u0e22\u0e37\u0e14\u0e2d\u0e32\u0e22\u0e38\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e21\u0e35\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e<\/p>","protected":false},"author":2,"featured_media":12408,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[64],"tags":[62,907,902,908,520,384,338,97,67,896,117,260,93,895,90],"class_list":["post-12398","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-liver-cancer","tag-chg-cancer-center","tag-hcc-treatment","tag-immunotherapy","tag-sorafenib-lenvatinib","tag-systemic-therapy","tag-targeted-therapy","tag-338","tag-97","tag-liver-cancer","tag-896","tag-117","tag-260","tag-93","tag-895","tag-90"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/12398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/comments?post=12398"}],"version-history":[{"count":0,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/12398\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media\/12408"}],"wp:attachment":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media?parent=12398"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/categories?post=12398"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/tags?post=12398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}