{"id":13210,"date":"2025-04-03T18:56:29","date_gmt":"2025-04-03T11:56:29","guid":{"rendered":"https:\/\/chgcancercenter.com\/?p=13210"},"modified":"2025-04-03T19:29:23","modified_gmt":"2025-04-03T12:29:23","slug":"adc-therapy-targeted-cancer-treatment","status":"publish","type":"post","link":"https:\/\/chgcancercenter.com\/en\/adc-therapy-targeted-cancer-treatment\/","title":{"rendered":"ADCs Target Cancer, Reduce Side Effects"},"content":{"rendered":"
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ADCs Target Cancer, Reduce Side Effects<\/strong><\/span><\/h1>

ADCs or Antibody-Drug Conjugates are a breakthrough in cancer treatment technology. They combine the precision of monoclonal antibodies with the powerful effects of chemotherapy, aiming to kill cancer cells with minimal harm to healthy tissue.<\/p>

What Are ADCs?<\/b><\/span><\/h2>

ADCs are made by attaching a monoclonal antibody (that specifically targets cancer cell proteins) to a potent chemotherapy drug via a chemical linker. This allows the drug to be released only inside the cancer cell, improving precision and minimizing side effects.<\/p>

How Do ADCs Work?<\/b><\/span><\/h2>
  1. Targeting: The antibody part of the ADC binds to a protein found specifically on the surface of cancer cells.<\/li>
  2. Internalization: Once bound, the entire ADC is absorbed into the cancer cell.<\/li>
  3. Drug Release: The linker breaks down inside the cell, releasing the toxic drug that kills the cancer cell from within.<\/li><\/ol>

    Advantages of ADCs<\/b><\/span><\/h2>