{"id":13538,"date":"2025-05-14T00:42:17","date_gmt":"2025-05-13T17:42:17","guid":{"rendered":"https:\/\/chgcancercenter.com\/?p=13538"},"modified":"2025-05-14T01:15:16","modified_gmt":"2025-05-13T18:15:16","slug":"high-dose-chemotherapy-treatment","status":"publish","type":"post","link":"https:\/\/chgcancercenter.com\/en\/high-dose-chemotherapy-treatment\/","title":{"rendered":"High-dose Chemotherapy for Resistant Cancers"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"13538\" class=\"elementor elementor-13538\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53eb7dc6 e-flex e-con-boxed e-con e-parent\" data-id=\"53eb7dc6\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1995faba elementor-widget elementor-widget-text-editor\" data-id=\"1995faba\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1><strong><span style=\"font-size: 24pt;\">High-dose Chemotherapy for Resistant Cancers<\/span><\/strong><\/h1><h2><span style=\"font-size: 18pt;\"><b>What is High-dose Chemotherapy?<\/b><\/span><\/h2><p class=\"translation-block\">High-dose chemotherapy is the administration of many times larger doses of anticancer drugs than normal. The purpose of the treatment is to<\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\">Eliminate cancer cells that are resistant to conventional treatments<\/li><li style=\"font-weight: 400;\" aria-level=\"1\">Destroy cancer at the molecular level<\/li><\/ul><p class=\"translation-block\">Used in conjunction with bone marrow\/stem cell transplantation to help the body recover after bone marrow destruction<\/p><h3><span style=\"font-size: 14pt;\"><b>What type of patients is it used for?<\/b><\/span><\/h3><p><span style=\"font-weight: 400;\">High-dose chemotherapy is often used in the following cases:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/chgcancercenter.com\/en\/can-leukemia-be-cured\/\"><span style=\"font-weight: 400;\">Leukemia<\/span><\/a><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/chgcancercenter.com\/en\/lymphoma-itching-skin-care-relief\/\"><span style=\"font-weight: 400;\">Lymphoma<\/span><\/a><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Multiple Myeloma<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Testicular cancer resistant to conventional chemotherapy<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some childhood cancers, such as advanced neuroblastoma<\/span><\/li><\/ul><h3><span style=\"font-size: 14pt;\"><b>Mechanism of action<\/b><\/span><\/h3><p><span style=\"font-weight: 400;\">Using high doses of chemotherapy<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Destroys more DNA than normal in cancer cells<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increases the chance of shrinking the tumor or temporarily suppressing the cancer<\/span><\/li><\/ul><p class=\"translation-block\">Disadvantages: Severely affects the bone marrow. A bone marrow transplant is required to help the body recover.<\/p><h2><span style=\"font-size: 18pt;\"><b>Risks and Side Effects<\/b><\/span><\/h2><p><span style=\"font-weight: 400;\">High-dose chemotherapy has more severe side effects than usual, such as:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe neutropenia (risk of severe infection)<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia, thrombocytopenia<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea, vomiting, diarrhea<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Hair loss, dry skin, mouth ulcers<\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vital organs such as the liver, kidneys or heart may be affected.<\/span><\/li><\/ul><p><span style=\"font-weight: 400;\">Therefore, it must be under the care of a specialist doctor and in a hospital that is ready to handle complications.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-03fc15b e-flex e-con-boxed e-con e-parent\" data-id=\"03fc15b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36c3cc6 elementor-widget elementor-widget-text-editor\" data-id=\"36c3cc6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"font-size: 18pt; color: #000000;\"><b>Advantages of High-dose Chemo<\/b><\/span><\/h2><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400; color: #000000;\">Increased chance of disease control or remission<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\" class=\"translation-block\">Used in patients who are resistant to standard-dose chemotherapy<\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"color: #000000;\">As part of a complex treatment plan, such as in combination with stem cells<\/span><\/li><\/ul><h2><span style=\"font-size: 18pt; color: #000000;\"><b>Must be done at a specialized hospital<\/b><\/span><\/h2><p class=\"translation-block\">High-dose chemotherapy must be done in a cancer center or bone marrow transplant center with complete personnel and equipment because the patient will have a very low immune system and must be closely monitored.<\/p><h2><span style=\"font-size: 18pt; color: #000000;\"><b>summarize<\/b><\/span><\/h2><p class=\"translation-block\">High-dose chemotherapy is the administration of a higher concentration of cancer drugs than normal in order to control advanced or refractory disease. It is a method that requires weighing the results against severe side effects, so it should be managed by a specialist and carefully planned with the family.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a93b92e e-flex e-con-boxed e-con e-parent\" data-id=\"a93b92e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-93ea625 elementor-widget elementor-widget-image\" data-id=\"93ea625\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"640\" height=\"426\" src=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1.jpg\" class=\"attachment-large size-large wp-image-13550\" alt=\"\u0e2d\u0e34\u0e19\u0e42\u0e1f\u0e01\u0e23\u0e32\u0e1f\u0e34\u0e01\u0e2a\u0e23\u0e38\u0e1b\u0e02\u0e49\u0e2d\u0e21\u0e39\u0e25\u0e40\u0e04\u0e21\u0e35\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e02\u0e19\u0e32\u0e14\u0e2a\u0e39\u0e07 (High-dose Chemotherapy) \u0e04\u0e23\u0e2d\u0e1a\u0e04\u0e25\u0e38\u0e21\u0e04\u0e27\u0e32\u0e21\u0e2b\u0e21\u0e32\u0e22 \u0e01\u0e25\u0e44\u0e01\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19 \u0e1c\u0e25\u0e02\u0e49\u0e32\u0e07\u0e40\u0e04\u0e35\u0e22\u0e07 \u0e02\u0e49\u0e2d\u0e14\u0e35 \u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e43\u0e0a\u0e49\u0e43\u0e19\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e17\u0e35\u0e48\u0e14\u0e37\u0e49\u0e2d\u0e22\u0e32\" srcset=\"https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1.jpg 800w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1-300x200.jpg 300w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1-768x512.jpg 768w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1-18x12.jpg 18w, https:\/\/chgcancercenter.com\/wp-content\/uploads\/2025\/05\/High-dose-Chemotherapy-for-Resistant-Cancers1-600x400.jpg 600w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-32e8f1d e-flex e-con-boxed e-con e-parent\" data-id=\"32e8f1d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18e9011 elementor-widget elementor-widget-ct_text_editor\" data-id=\"18e9011\" data-element_type=\"widget\" data-widget_type=\"ct_text_editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"ct_text_editor-18e9011\" class=\"ct-text-editor wow fadeInUp\" data-wow-delay=\"ms\">\n\t<div class=\"ct-item--inner\">\n\t\t<div class=\"ct-inline-css\"  data-css=\"\t        \t\t\t\">\n\n\t    <\/div>\n\t\t<div class=\"ct-text-editor elementor-clearfix\">\n\t\t\t<p class=\"translation-block\">For inquiry, please call <a href=\"tel:0638166058\" target=\"_self\">+66638166058<\/a><\/p>\t\t\n\t\t<\/div>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc4a6ee e-flex e-con-boxed e-con e-child\" data-id=\"cc4a6ee\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c0616b5 e-con-full e-flex e-con e-child\" data-id=\"c0616b5\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e7c50bd elementor-widget elementor-widget-text-editor\" data-id=\"e7c50bd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: lineseedsansth;\">Request consultation for treatment plan<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9058c76 e-con-full e-flex e-con e-child\" data-id=\"9058c76\" data-element_type=\"container\" data-settings=\"{&quot;position&quot;:&quot;absolute&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d1e4874 elementor-widget elementor-widget-text-editor\" data-id=\"d1e4874\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/lin.ee\/sx9JJLJ\"><img decoding=\"async\" class=\"\" src=\"https:\/\/scdn.line-apps.com\/n\/line_add_friends\/btn\/th.png\" alt=\"\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e19\" width=\"115\" height=\"36\" border=\"0\" \/><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-549157e e-flex e-con-boxed e-con e-child\" data-id=\"549157e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\u0e40\u0e04\u0e21\u0e35\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e02\u0e19\u0e32\u0e14\u0e2a\u0e39\u0e07 (High-dose chemotherapy) \u0e04\u0e37\u0e2d \u0e01\u0e32\u0e23\u0e43\u0e0a\u0e49\u0e22\u0e32\u0e43\u0e19\u0e1b\u0e23\u0e34\u0e21\u0e32\u0e13\u0e21\u0e32\u0e01\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e23\u0e31\u0e01\u0e29\u0e32\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e17\u0e35\u0e48\u0e44\u0e21\u0e48\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e15\u0e48\u0e2d\u0e27\u0e34\u0e18\u0e35\u0e1b\u0e01\u0e15\u0e34 \u0e43\u0e0a\u0e49\u0e04\u0e39\u0e48\u0e01\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1b\u0e25\u0e39\u0e01\u0e16\u0e48\u0e32\u0e22\u0e44\u0e02\u0e01\u0e23\u0e30\u0e14\u0e39\u0e01<\/p>","protected":false},"author":2,"featured_media":13554,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[159],"tags":[62,122,97,177,734,1223,175,284,1222,260,93,1224,115,1221,90],"class_list":["post-13538","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatment-technology","tag-chg-cancer-center","tag-122","tag-97","tag-177","tag-734","tag-1223","tag-175","tag-284","tag-1222","tag-260","tag-93","tag-1224","tag-115","tag-1221","tag-90"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/13538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/comments?post=13538"}],"version-history":[{"count":0,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/posts\/13538\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media\/13554"}],"wp:attachment":[{"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/media?parent=13538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/categories?post=13538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/chgcancercenter.com\/en\/wp-json\/wp\/v2\/tags?post=13538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}